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Find a Clinical Trial

The American Lung Association recommends considering clinical trials as soon as you are diagnosed, and every time you must make a treatment decision. Clinical trials are carefully monitored scientific research studies that test how well new medical approaches work in people. Each study answers scientific questions and tries to find better ways to prevent, screen for, diagnose or treat a disease.

MK-6070-002

Researchers want to know if giving gocatamig, I-DXd, and gocatamig with I-DXd or durvalumab can treat SCLC that did not respond or stopped responding to a prior treatment. The goals of this study are to learn 1) if gocatamig alone, I-DXd alone, and gocatamig with I-DXd or durvalumab are safe and well tolerated and 2) if people who receive gocatamig alone, I-DXd alone, and gocatamig with I-DXd or durvalumab have their SCLC get smaller or go away.

MK-6070-003

The goals of this study are to learn 1) about the safety of combining gocatamig and I-DXd and if people tolerate them together and 2) if people who receive gocatamig and I-DXd have ES-SCLC respond, which means the cancer gets smaller or goes away.

MTAP-0009 (CA240-0009)

The purpose of this study is to evaluate the safety and efficacy of Navlimetostat (BMS-986504) monotherapy in participants with advanced or metastatic Non-small Cell Lung Cancer (NSCLC) with homozygous MTAP deletion after progression on prior therapies.

MTAP-0029 (CA240-0029)

The purpose of this study is to compare the clinical benefit of the combination of Navlimetostat (BMS-986504) (a selective MTA-cooperative inhibitor of PRMT5) plus pembrolizumab and chemotherapy versus placebo plus pembrolizumab and chemotherapy in first-line metastatic non-small cell lung cancer participants with homozygous MTAP deletion

OCEAN-1

The primary purpose is to evaluate the safety and efficacy of NAL ER for the treatment of chronic cough in participants with Idiopathic Pulmonary Fibrosis (IPF).

Open-label Multi-Cohort 1b/2

The study will address the hypothesis that telisotuzumab adizutecan in combination with a PD-1 immune check point inhibitor (budigalimab or pembrolizumab) can be safely administered and telisotuzumab adizutecan in combination with pembrolizumab will provide a favorable risk/benefit profile compared to the SOC control (pembrolizumab and platinum doublet) in subjects with locally advanced/metastatic NSq NSCLC who have no prior systemic therapy for advanced disease and who are EGFR WT and have no known other actionable genomic alterations.

Optimizing self-management COPD treatment through the American Lung Association Helpline

The current study will test the feasibility of using an engineering-inspired study design to identify effective COPD self-management treatment components.

Phase 2, Open-Label, Study of the Combination of RMC-4630 and Sotorasib for Non-Small Cell Lung Cancer

The purpose of this study is to evaluate the antitumor effects of sotorasib and RMC-4630 subjects with KRASG12C mutant NSCLC that have not been exposed to prior therapy with KRASG12C inhibitors and/or SHP2 inhibitors.

RELA-1093 (CA224-1093)

The purpose of this study is to compare the efficacy of Nivolumab and Relatlimab in combination with chemotherapy to Pembrolizumab with Chemotherapy in participants with stage IV or recurrent Non-squamous Non-small Cell Lung Cancer with PD-L1 expression ≥ 1%

ROSETTA Lung-201

A study to evaluate Pumitamig versus Durvalumab following concurrent chemoradiation therapy in participants with unresectable stage III Non-small Cell Lung Cancer (NSCLC).
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See how your institution or organization can add its study to our lung disease clinical trials listing.

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