KANDLELIT-004

A Study of MK-1084 Plus Pembrolizumab in Participants With KRAS G12C Mutant, Metastatic Non-small Cell Lung Cancer With Programmed Cell Death Ligand 1 Tumor Proportion Score ≥50%

Study Name:
A Study of MK-1084 Plus Pembrolizumab in Participants With KRAS G12C Mutant, Metastatic Non-small Cell Lung Cancer With Programmed Cell Death Ligand 1 Tumor Proportion Score ≥50%

Targeted Disease(s):
Lung Cancer

Purpose of Study:

This is a study evaluating the efficacy and safety of calderasib with pembrolizumab as first-line treatment in participants with locally advanced or metastatic non-small cell lung cancer (NSCLC) with identified Kirsten rat sarcoma viral oncogene homolog G12C (KRAS G12C) mutation and programmed cell death ligand 1 (PD-L1) tumor proportion score (TPS) ≥50%.

Study Dates:
May 24, 2024 - February 18, 2031

Type of Study:
Pre-Market

Study Design:
Controlled Design

Study Location:
Nationwide

Funding Source:
Merck Sharp & Dohme LLC

Contact:

1-888-577-8839
[email protected]

ClinicalTrails.gov Identifier:
NCT06345729

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