Find a Clinical Trial | American Lung Association

EXHALE-4

The purpose of this study, EXHALE-4, is to assess the efficacy and safety of Dexpramipexole, an oral eosinophil maturation inhibitor, in patients ≥ 12 years of age with inadequately controlled moderate-severe eosinophilic asthma (GINA Step 3, 4, or 5). The primary endpoint of this study is change in lung function (FEV1) from baseline.

Gates MRI- COD-01-T01-01 Amendment 1

A randomized, controlled, Phase 2b study to evaluate safety and efficacy of rivaroxaban(Xarelto®) for high risk people with mild COVID-19.

HARBOR Study

The HARBOR Study is evaluating the safety and effectiveness of a potential medicine (HZN-825) that may slow disease progression in participants with idiopathic pulmonary fibrosis (IPF).

IMPALA2

To discover whether molgramostim (inhaled GM-CSF) is safe to take and can help to reduce the symptoms of (autoimmune pulmonary alveolar proteinosis ) aPAP.

Improving Medication Adherence with Telehealthcare Medication Therapy Management to Change Health Outcomes in Adolescents and Young Adults with Asthma (MATCH)

The ACRC network is studying whether having regular telehealth appointments with a pharmacist using a study provided tablet or a person’s smart phone or computer will help adolescents and young adults with asthma to gain control of asthma symptoms and improve inhaler effectiveness.

INSIGNIA PH-COPD

A phase 2a randomized, placebo-controlled clinical study to evaluate the efficacy and safety of MK5475 in adults with pulmonary hypertension associated with Chronic Obstructive Pulmonary Disease.

KEAPSAKE

A Phase 2 Randomized, Multicenter, Double-Blind Study of the Glutaminase Inhibitor Telaglenastat with Pembro and CTX Versus Placebo with Pembro and CTX in 1L, Metastatic KEAP1/NRF2-Mutated, Nonsquamous NSCLC

KEYLYNK-012

This study is looking at how pembrolizumab with chemotherapy and radiation followed by pembrolizumab plus olaparib (or placebo for olaparib) works compared to chemotherapy and radiation followed by durvalumab.

KEYLYNK-013

This clinical trial is trying to find out if a combination of study drugs can help stop or slow down this type of cancer.

LEARN

To compare the treatment effect between at-home mobile spirometry and in-clinic spirometry in participants with moderate asthma, receiving a long-acting beta agonist (LABA) treatment.

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