Souheil El-Chemaly, M.D., MPH

Home
Research & Reports
About Our Research
Previously Funded Researchers
Souheil El-Chemaly, M.D., MPH

Research Project:
Identifying the Mechanisms Underlying Hermansky-Pudlak Syndrome

Research Topic:

clinical research

Research Diseases:

cystic fibrosis
pulmonary fibrosis

Hermansky-Pudlak syndrome (HPS) is a rare inherited disease which causes scarring of the lungs with limited treatment options. We will explore how HPS fibroblasts differ from those in normal lungs and whether treatment can make them behave like normal fibroblasts. These studies will be performed in zebrafish embryos, a new model for studying HPS pulmonary fibrosis which may have use in identifying new treatment targets. Understanding the underlying mechanisms of HPS may accelerate the discovery of therapies for more common lung diseases like cystic fibrosis and idiopathic pulmonary fibrosis.

Page last updated: June 7, 2024

Join the Patient & Caregiver Network

How to Help People Quit

10 Tips to Protect Yourself from Unhealthy Air

State of the Air Key Findings

Become an Advocate

Register for a LUNG FORCE Walk

Double Your Gift

Souheil El-Chemaly, M.D., MPH

2X Your Lifesaving Impact

Make a Donation

Become a Lung Health Insider

Select Your Location

Change Language

Lung HelpLine

1-800-LUNG-USA