Phosphoenolpyruvate depletion mediates both growth arrest and drug tolerance of Mycobacterium tuberculosis in hypoxia – Proceedings of the National Academies of Science

Dr. Hyungjin published this study finding that adding the molecule Phosphoenolpyruvate (PEP) to the current TB drug regimen helps fight against dormant, non-replicating tuberculosis which might be hiding within the body’s cells. These findings will help to improve the treatment effect of drugs. Dr. Eoh received the American Lung Association’s 2020-2021 Innovation Award for his work in tuberculosis.