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  5. Chronic exposure to carbon black ultrafine particles reprograms macrophage metabolism and accelerate

Chronic exposure to carbon black ultrafine particles reprograms macrophage metabolism and accelerates lung cancer

ScienceAdvances | November 16, 2022

This study found that ultrafine particles in cigarette smoke alter the metabolism of immune cells, drastically reducing immune function in the lungs. This is important because it shows how lung cancer is accelerated in people who smoke heavily, and can eventually lead to new treatments to improve immune function and slow or prevent the progression of lung cancer. Coauthor Xiaoyi Yuan was awarded the Lung Association Catalyst Award for her work in lung inflammation in ARDS.
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