Alternative splicing of CEACAM1 by hypoxia-inducible factor–1α enhances tolerance to hepatic ischemia in mice and humans

This study found that a glycoprotein called CEACAM1 protects liver function after liver transplant. This is important because CEACAM1 mRNA expression can potentially be a marker of liver quality and eventual treatment outcomes, and an excellent example of how research performed by a lung scientist can have impact in other disease states and organ systems. Co-Author Xiaoyi Yuan, PhD was awarded the Lung Association Catalyst Award for her work evaluating mRNA as a therapeutic target for ARDS.