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Clinical Trials

Zinc Acetate to Improve Chronic Cough (ZICO)

Institution:

Nationwide

Type:

Multi-Center Trial

Purpose:

The American Lung Association Airways Clinical Research Center (ACRC) network is evaluating measurements of cough symptoms and the impact of cough on quality of life for people with chronic cough. A chronic cough is a cough that lasts at least 8 weeks, but often much longer. Chronic cough is common, affecting 9-12% of the population. It can have a negative impact on quality of life and may lead to social isolation, lack of sleep, and chronic fatigue. Some people find that their chronic cough gets better when they take medicines for asthma, gastroesophageal reflux (GERD), or sinus problems. Other people are not helped by these or other medicines. People with a cough that does not respond to treatments are said to have chronic refractory cough.

The Pilot of Zinc Acetate to Improve Chronic Cough (ZICO) study is testing whether zinc acetate is safe and tolerable to use for treating chronic refractory cough. ZICO is a 9-week study with 5 clinic visits and 1 phone visit. Patients will be asked to fill out a daily Cough Diary while in the study. At visits, patients will do breathing tests, complete questionnaires and have their blood drawn.

Men and women age 18 or older with chronic cough are eligible to enroll in the ZICO study at five of the ACRC clinical centers: National Jewish Health (Denver, Colorado), Saint Vincent Airways Clinical Research Center (Indianapolis, Indiana), Washington University (Saint Louis, Missouri), Mt. Sinai Medical Center (New York, New York), and Duke University (Durham, North Carolina).

Dates:

September 1, 2016 - December 30, 2019

Disease:

COPD

Contact:

See recruiting centers
[email protected]

Below is a list of recruiting centers:

Colorado
National Jewish Health
1400 Jackson Street
Room K-239
Denver, CO 80206
Contact: Juno Pak, Lead Coordinator
(303) 398-1443
[email protected]

Indiana
St. Vincent Airways Clinical Research Center
8333 Naab Road
Suite 301
Indianapolis, IN 46260
Contact: Ellen Looney, BS, Lead Coordinator
(317) 338-8030
[email protected]

Missouri
Washington University School of Medicine
Division of Pulmonary and Critical Care Medicine
660 S. Euclid Avenue
Campus Box 8052
St. Louis, Missouri 63110
Contact: Jaime J. Tarsi, RN, MPH, Lead Coordinator
(314) 747-3074
[email protected]

New York
Icahn School of Medicine
Mount Sinai National Jewish Health Respiratory Institute
One Gustave L. Levy Place
Box 1118
New York, New York 10029
Contact: 
Chelsea Chung, Clinical Research Coordinator
(212) 241-8655 
[email protected]

North Carolina
Duke Asthma Allergy Airway Center
1821 Hillandale Road
Suite 25A
Durham, North Carolina 27705
Contact: Catherine Foss, BS, RRT, RPFT, CCRC, Lead Coordinator
(919) 479-0861
[email protected]

Missouri
Washington University School of Medicine
Division of Pulmonary and Critical Care Medicine
660 S. Euclid Avenue
Campus Box 8052
St. Louis, Missouri 63110
Contact: Jaime J. Tarsi, RN, MPH, Lead Coordinator
(314) 747-3074
[email protected]

New York
Icahn School of Medicine
Mount Sinai National Jewish Health Respiratory Institute
One Gustave L. Levy Place
Box 1118
New York, New York 10029
Contact: 
Chelsea Chung, Clinical Research Coordinator
(212) 241-8655 
[email protected]

North Carolina
Duke Asthma Allergy Airway Center
1821 Hillandale Road
Suite 25A
Durham, North Carolina 27705
Contact: Catherine Foss, BS, RRT, RPFT, CCRC, Lead Coordinator
(919) 479-0861
[email protected]

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