Asthma research helps us understand how the disease is caused, how it develops and how it is best treated. Research can improve the quality of everyday life for those diagnosed with asthma.
The American Lung Association is committed to funding asthma research. Our Awards and Grants Program funds top-notch researchers at important career crossroads to gain long-term commitment to lung health and disease research. Without the life-long dedication of lung researchers, important and much-needed discoveries would not be possible. In addition to the Awards and Grants Program, the Lung Association funds the Airways Clinical Research Centers Network, which implements patient-centered clinical trials, and has helped to change the nature of asthma patient care since its inception in 2000.
Some of the current topics American Lung Association funded researchers are investigating include understanding the immune system’s role in asthma, the effect of mold on severe asthma; improving treatment of severe asthma in children, and studying genes and their role in controlling the immune response. We believe that all of these studies could lead to improved therapy and quality of life for people with asthma.
Thanks to the medical breakthroughs led by Lung Association researchers and their colleagues, we have made significant contributions to the field of asthma. Below are some of our current asthma researchers and their studies. Meet the entire research team and learn more about the research we fund.
Asthma Research Studies
See some of the current research projects we are funding:
- Yen-Hua Chen, Ph.D.Role of Arginase metabolism in innate lymphoid cell-mediated lung inflammationAmerican Lung Association researcher Yen-Hua Chen is studying how cell-intrinsic metabolic factors, specifically Arginase metabolism, regulate ILC2 function in promoting lung disease pathogenesis.
- Amy Firth, Ph.D.Harnessing Power of a Protein to Improve Lung Repair Following InjuryAmerican Lung Association researcher Amy Firth is studying how Claudin 18.1 influences function of airway stem cells, which are able to differentiate into specialized cell types to promote repair after injury.
- Hong Ji, Ph.D.Seeking Personalized Treatment for Severe Asthma in ChildrenAmerican Lung Association researcher Hong Ji is identifying biological mechanisms that switch genes on and off for difficult-to-treat childhood asthma and investigate how they contribute to the diversity of patients' disease and response to treatment.
- Monica Lawrence, M.D.Targeting Neutrophils in Severe Childhood AsthmaAmerican Lung Association researcher Monica Lawrence will examine the expression and function of the receptor for a protein called interleukin-5 (IL-5R) on the surface of airway neutrophils.
- Amanda Poholek, Ph.D.Protein Holds Clue to Allergic Airway InflammationAmerican Lung Association researcher Amanda Poholek is investigating the environmental factors that lead to the activation of Blimp-1 and how Blimp-1 causes T cells to drive allergic asthma.
Airways Clinical Research Centers
The American Lung Association Airways Clinical Research Centers (ACRC) Network is the nation's largest not-for-profit network of clinical research centers dedicated to asthma and chronic obstructive pulmonary disease (COPD) treatment research, attracting some of the best investigators nationwide. The ACRC Network conducts large clinical trials that will directly impact patient care for COPD and asthma. Meet our Principal Investigators, see where our centers are located and learn more about some of the important research findings from the ACRC.
Reviewed and approved by the American Lung Association Scientific and Medical Editorial Review Panel. Last reviewed June 5, 2018.
Page Last Updated: June 15, 2018