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Pulmonary function tests (PFTs) have long been used to diagnose and manage lung disease. You may have heard of spirometry, the most performed PFT, used to help determine if your lung function is within a normal range. If it isn’t, then your healthcare provider will look for reasons why and it may mean that you have a lung disease. If so, you will continue to have PFTs while being treated for your disease to help determine how well the treatment is working.

Knowing how vital testing and subsequent results are for disease management, employment and disability, a task force of healthcare providers took a hard look at how the results were being calculated and came up with a new standardized approach for interpreting results, which has been endorsed by the American Thoracic Society and European Respiratory Society.

The new results prioritize a standardized approach and a race-neutral focus. Let’s break down what that means for you.

Standardization of Pulmonary Function Tests using Z-Scores

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Understanding Pulmonary Function Tests

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Pulmonary function tests or PFTS help show how well your lungs are working. Your healthcare provider may recommend that you get this test to help figure out why you were feeling short of breath or if you cough or wheeze a lot.

There are three parts of a PFT. Spyometry, lung volumes, and diffusing capacity.

Spyometry measures how well you can breathe air out, similar to deflating a full balloon. Lung volumes show how much air your lungs can hold, much like seeing how much a balloon can fill up. The fusing capacity measures how well gas moves from your lungs into your blood.

For the most accurate results, you'll be asked to repeat parts of the PFT a few times in your test day. After the test, you'll receive a report of your PFT results. They'll be summarized into a zcore to provide a precise comparison of your score compared to what's expected for people of your age, sex, and height.

Your healthcare provider will use these results to determine if your lungs are healthy. For some people whose results are near or below the expected range, zcores can indicate that more evaluation is needed to look for a lung problem.

Zcores are one part of how we define your lung function. This new consistency of care will help empower you to know your numbers and better understand your lung health.

Repeated PFTS help your health care provider monitor your lung function over time and identify any new issues earlier. Your healthcare provider can explain what your results mean using your Zcore to classify your lung health and suggest next steps and treatment options based on your test findings.

Because if you can't breathe, nothing else matters. Learn more at lung.org.

“To make PFTs even more accurate, healthcare providers are now using something called z-scores,” says A. Ian Wong, a physician at Durham VA Medical Center. “We used to report lung function as a percent of what we would predict your lung function to be, but now we’ve found a better way to do it.” Z-scores describe how common your lung function numbers are. It sounds a bit similar to the old way, but this slightly different comparison helps providers better understand if your results are within a normal range or if there is something going on that needs more attention.

If your lung function is near or below the expected range, it is an indicator that more evaluation is needed. And if you have low lung function, your z-score helps decide how severe your lung disease is. Knowing this helps providers determine the best treatment at the right time for you.

Another benefit of the change is that z-scores are a global indicator of lung function so that makes it easier to receive consistent care around the world. It’s kind of like how most of the world uses the metric system to measure in meters and grams, but the United States still uses customary units like inches and feet. With two different measuring systems, it’s harder to compare. Because of this, healthcare in the United States always uses the metric system to avoid confusion about medication doses or patient weight. Standardization of z-scores at a global level helps improve patient care.

“In summary, z-scores are a new and consistent way to define your lung function.” Says Dr. Wong. “You should know your numbers to help you better understand your treatment goals and your lung health. Your doctor can help answer any questions you have about this.”

Race-neutral Pulmonary Function Tests

PFTs aren’t used exclusively for patients experiencing symptoms of or having been diagnosed with lung disease. Sometimes PFTs are required by an employer – for example the military or the fire department – to ensure that your lung function remains healthy during employment. There are some cutoffs with certain jobs that require your lung function to be within a particular range to maintain employment, making accurate PFT testing essential.

Another example of how important accurate test results are is that disability claims are approved or declined based, in part, on your PFT results. Or you may qualify – or not – for certain treatments such as a lung transplant based on your results. But how we previously calculated these results was found to be inequitable and a new system emerged.

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Understanding Changes to Breathing Tests

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Breathing tests, also called pulmonary function tests, are being evaluated with new reference equations. You may have heard about these new reference equations, but what does that mean, and why should you care?

Newer science has taught us that it isn't best practice to include race when evaluating the results of breathing tests. Using race may lead to misrepresentation of lung health severity, particularly in people of color. So, moving forward, your race will not be noted.

This change could affect whether you qualify for certain treatments such as lung surgery or a lung transplant. It might also impact employment for jobs where breathing tests are required or determine if you qualify for disability benefits.

For example, if your numbers are now considered less severe, you are more likely to meet employment criteria, but you may not qualify for disability.

Reference equations help healthcare providers determine if you have lung disease and how severe it is. When you get breathing tests, we measure your numbers and then compare them to a group of healthy people with a similar age, height, and sex assigned at birth using reference equations.

We used to consider race in this comparison, but new reference equations exclude race to make breathing test interpretation more equitable for everyone.

For most people, how we interpret your breathing tests won't change. But people whose numbers are near cut offs may shift into more or less severe categories.

These can seem like big changes, but it is important to remember your breathing test numbers and how they are interpreted are only a small part of understanding your lung health. Many other factors are considered in making a diagnosis or determining your treatment plan.

You should talk to your healthcare provider to guide you through these changes and what they mean for you.

Learn more at lung.org.

“It is of utmost importance to conduct PFTs in an equitable and respectful manner,” says Aparna Balasubramanian, a physician at Johns Hopkins. “After reviewing the data, defining normal lung function by race was found to hinder appropriate interpretation of PFT results so it was removed from reference equations.”

In fact, it was found to be that the use of race-based calculations can lead to inaccurate diagnoses and perpetuate health disparities, particularly for minority populations. The medical community was alarmed to learn that including race as part of the prediction of normal lung function was potentially leading to an underdiagnosis of lung disease in minority populations. It also has the potential of contributing to systemic racism within healthcare.

“Simply put, including race in reference equations for PFTs caused harm,” says Dr. Balasubramanian, “Moving forward, medical organizations recommend using race-neutral equations so that lung function is assessed based only on age, sex assigned at birth and height.”

Researchers and healthcare providers are constantly looking at new and better ways to prevent, diagnose and treat disease. Data-based changes are a good thing, even though they can be a bit confusing at first. You can reach out to your healthcare provider for more information on your PFT results and how they impact your treatment plan. You can also call the American Lung Association’s Lung HelpLine at 800-LUNGUSA (option 2) to ask our lung health experts your questions about pulmonary function tests. Learn more about pulmonary function tests at Lung.org/pft.

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