Lung Health Cohort Study: The Research

Research is equal parts art and science. It strikes a delicate balance in the search for answers, the quest for solutions.

The common facts of today are the products of yesterday's research.- Duncan MacDonald

About the Study

Funded by the Heart, Lung and Blood Institute, the American Lung Association Lung Health Cohort Study, in partnership with Northwestern University and Johns Hopkins University, is the first-ever federally funded U.S. longitudinal cohort of millennials. With study sites across the U.S., we are enrolling 4,000 young and healthy adults, from 25 to 35 years old, to piece together the complicated puzzle of lung disease. The results of this multi-year study, anticipated to be synonymous to the cholesterol discovery for cardiovascular health, will help shift pulmonary medicine from reactive treatment to preventive lung health care.

BeLUNG to Something Bigger

Study Goals

Our Lung Health Study goals include determining whether:

  • Modifiable exposures and risk factors are associated with lower lung function and greater burden of respiratory symptoms in young adults
  • CT-measured small airways and lung injury are associated with lower lung function and greater burden of respiratory symptoms in young adults
  • Nasal cells and selected blood biomarkers are differentially associated with CT-measured small airways and lung injury in young adults

To accomplish our objectives, we are collaborating with scientists nationwide at our Airways Clinical Research Centers (ACRC) Network and beyond to make the best use of the collected data.

Study Documents - Coming Soon

Cohort details geared toward the scientific community.

Exam Documents:

  • Study synopsis
  • Protocol
  • Consent
  • MOPs

Data & Sample Collection:

  • Forms synopsis
  • Actigraphy
  • Spirometry (in-clinic & home)v
  • Imaging
  • Biospecimens

Study Policies:

  • Ancillary studies
  • Data sharing
  • Publications & presentations

The American Lung Association (ALA) Lung Health Cohort

This research has been approved by the Johns Hopkins Institutional Review Board

Protocol: IRB00236497

Principal Investigator: Elizabeth Sugar

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