LC-MS/MS method for proline-glycine-proline and acetylated proline-glycine-proline in human plasma

This study discovered a new and reliable method to measure a peptide called proline-glycine-proline (PGP) in human plasma. This is important because PGP levels could be a potential biomarker for chronic lung disease and cancer, and this method could lead to disease detection earlier, and potentially be a therapeutic target. Senior Author J. Michael Wells MD was funded by an American Lung Association ACRC Pilot award.