Mycobacterium tuberculosis impairs human memory CD4+ T cell recognition of M2 but not M1- like macrophages

This study examined how and why certain types of T-cells (white blood cells that help the immune system fight germs), recognize and destroy cells infected with mycobacterium tuberculosis, the bacteria responsible for a tuberculosis infection. This research is critical to improve vaccines to protect against tuberculosis infections and reduce the risk of infectious lung disease. Senior author Steven M. Carpenter was awarded the American Lung Association Catalyst Award.