Teresa Allende-Aydillo Gomez, PhD

Teresa Allende-Aydillo Gomez, PhD

Icahn School of Medicine at Mount Sinai

Research Project:
Immunological Imprinting and Cross-reactive Immune Responses in COVID19

Grant Awarded:

  • COVID-19 Respiratory Virus Research Award

Research Topics:

  • clinical research
  • epidemiology
  • immunology immunotherapy

Research Diseases:

  • COVID-19
  • respiratory viruses

SARS-CoV-2 is a betacoronavirus that belongs to a large family of viruses capable of infecting both mammals and birds. Some of these viruses include the coronaviruses responsible for the common cold in humans. We have shown in the past that prior exposure to these common cold coronaviruses may result in the generation of cross-reactive immune responses upon SARS-CoV-2 infection. However, the impact of pre-existing immunity and cross-reactivity immune responses to other coronaviruses in SARS-CoV-2 is not totally clear. We will study how cross-reactive immune responses against multiple coronaviruses can impact SARS-CoV-2 immune responses. In a second step, we will use this information to identify and generate monoclonal antibodies with the ability to exhibit protection against multiple coronaviruses. Our research will help to develop human therapeutics against coronaviruses that can have pathogenic potential.  

Page last updated: October 10, 2023

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