Dr. Loren Denlinger is a physician-scientist and the inaugural William W. and Judith H. Busse Endowed Professor of Allergy and Asthma Research. She studies the risk factors for- and mechanisms of recovery from asthma exacerbations, with a mindset toward biomarker and therapeutic development. Dr. Denlinger's laboratory and clinical research group perform human challenge studies with inhaled allergens, rhinovirus inoculation, and/or research bronchoscopy, and have ongoing collaborations using functional lung imaging (see references below). She has participated in NHLBI Asthma Clinical Research Network (ACRN) and AsthmaNet network clinical trials since 2004, and am now the Principal Investigator for the Great Lakes Partnership within the Precision Interventions in Severe and/or Exacerbation-prone Asthma (PrecISE) Network. This focus on exacerbation pathophysiology and its consequences has led Dr. Denlinger to leadership roles within the AsthmaNet and Severe Asthma Research Program, serving as the Co-Chair of the Exacerbations Working Groups for both networks since 2010. Her interest in research participant safety has also led to a Clinical Chair role for the Data Monitoring Committee within the CTSA-funded UW Institute for Clinical and Translational Research. Finally, she directs the University of Wisconsin Advanced Asthma Care Clinic, which provides Allergy, Pulmonary and Pharmacy care for adults with severe asthma, utilizing a multidisciplinary visit structure to facilitate the development of coordinated care plans.