EEPD1 promotes repair of oxidatively-stressed replication forks

This study found that a gene called EEPD1 is critical to regular genetic function, replication, and repair of DNA, the processes of which are severely disrupted in cancer. This is important because targeting this gene in specific types of cancers could present a novel therapeutic target. Co-author Jac Nickoloff, PhD, was funded by the Lung Association Lung Cancer Discovery Award for his work in DNA damage in lung cancer treatments.
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