Moumita Ghosh, PhD

Moumita Ghosh, PhD

University of Colorado Denver

Research Project:
Identifying Lung Changes During Lung Cancer Development to Improve Early Detection

Grant Awarded:

  • Lung Cancer Discovery Award

Research Topic:

  • basic biologic mechanisms

Research Disease:

  • lung cancer

The goal of this project is to identify changes in the lung that occur during lung cancer development, to improve early detection. Epithelial stem/progenitor cells are critical for tissue repair, to maintain a healthy lung. Our pilot data showed that these cells are impaired in people with lung cancer, coinciding with an increased presence of immune cells. We will study epithelial progenitor cells, how their function is affected by their location relative to a tumor, and by the presence of immune cells. We will use lung tissues from patients with early-stage lung cancer. We expect to identify important factors that influence progenitor function. Our findings can be used for early detection or targeted to enhance progenitor function and constrain cancer formation.

Page last updated: January 26, 2023

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