Meredith McCormack, MD, MHS

Meredith McCormack, MD, MHS

Johns Hopkins University School of Medicine

Research Project:
Testing a Diabetes Drug in Obese Individuals With Asthma

Grant Awarded:

  • ACRC Pilot Grant

Research Topic:

  • social behavioral research

Research Disease:

  • asthma

Obese individuals with asthma continue to have limited treatment options and are often resistant to current first-line asthma therapies. Previous research suggests that metformin, the first-line treatment for type 2 diabetes, may be beneficial among patients with asthma and elevated body mass index. To define the role of metformin in treating asthma, a definitive, multicenter trial is needed. We will conduct a cross-sectional study of individuals with overweight/obesity and asthma who do not have a pre-existing indication for metformin, in order to define recruitment strategies. This is a necessary step to plan a definitive trial. The opportunity to repurpose an existing drug to treat individuals with asthma is novel and has potential to create a paradigm shift in our approach to obese individuals with asthma.

Page last updated: January 26, 2023

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