University of Pennsylvania
How Immune Cells Clear Legionnaire's Disease Bacteria from Lungs
Lung infections are a leading cause of disease and death in the United States. Designing strategies to combat lung infection requires a better understanding of how the immune system responds to such infection and controls it. Dr. Shin and her team hope to understand how immune cells detect bacterial infection in the lung and generate a successful response that clears the infection using the lung pathogen Legionella pneumophila, the causative agent of the severe bacterial pneumonia Legionnaire's disease.