This website uses cookies. By continuing you are agreeing to our privacy policy.

Toru Nyunoya, MD

Research Awards Nationwide Recipient (2013-2015)

Biomedical Research Institute of New Mexico, Albuquerque, NM
Cigarette Smoke Affects Lungs' "Biological Clock"
Biomedical Research Grant

Exposure to cigarette smoke increases the risk of emphysema. One possible mechanism may be that contents of smoke shorten the length of telomeres, the ends of chromosomes that control the process by which each cell ages. Dr. Nyunoya's hypothesis is that aldehyde dehydrogenase 3A1 (ALDH3A1), an enzyme used to detoxify reactive aldehydes contained in cigarette smoke may change the biological clock. His in vitro studies demonstrated that an increased amount of ALDH3A1 protects against DNA damage and cell death in response to cigarette smoke exposure. Based on the mechanisms identified by this research, he plans to develop a novel treatment for emphysema.

Red button with telephone
Ask An Expert

Questions about your lung health? Need help finding healthcare? Call 1-800-LUNGUSA.

Get help
Red button of two hand prints
We need your generous support

Make a difference by delivering research, education and advocacy to those impacted by lung disease.

Button of turquoise LUNG FORCE swirl

LUNG FORCE unites women and their loved ones across the country to stand together in the fight against lung cancer.

Get involved
Join the fight for healthy lungs and healthy air.
Donate Now.