Andrew Synn, M.D.
Beth Israel Deaconess Medical Center, Boston, MA
Clinical and Pathologic Validation of a Radiographic Biomarker of Pulmonary Vascular Disease
Disease that affects the pulmonary vessels is common in individuals with chronic lung conditions but can difficult to detect without invasive procedures. Which may limit treatment options. This project will evaluate the use of chest imaging to detect abnormalities in the pulmonary vessels. The first objective of this project is to determine whether these abnormalities in the pulmonary vessels are associated with worse heart and lung function in generally healthy adults. The second objective is to determine whether abnormalities in the pulmonary vessels actually reflect disease-related changes at the microscopic level in patients who had lung biopsies. Together, these objectives will help determine whether this new chest imaging method can be used to help detect pulmonary vascular disease in patients who are at-risk without the need for an invasive procedure.
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