Ji Yeon Kim, PhD | American Lung Association

Location Select your location

Ji Yeon Kim, PhD

Research Awards Nationwide Recipient (2014-2016)

UT-Southwestern Medical Center, Dallas, TX
Lung Cancer Mutations Increase Levels of Polyamines

Polyamines are naturally occurring molecules that are essential for cell growth. They can contribute to tumor growth and survival, but the way in which this occurs is unknown. We have found that polyamine content is dramatically increased by combinations of the three of the most common mutations in lung cancer—P53, KRAS, and LKB1. We will study how these mutations elevate polyamine levels in lung cancer cells. We will then extend these findings to mouse and human lung tumors. Our research has the potential to provide a foundation for novel therapeutic strategies in lung cancer.

Ask An Expert

Questions about your lung health? Need help finding healthcare? Call 1-800-LUNGUSA.

Get help
We need your generous support

Make a difference by delivering research, education and advocacy to those impacted by lung disease.

What is LUNG FORCE?

LUNG FORCE unites women and their loved ones across the country to stand together in the fight against lung cancer.

Get involved
Join the fight for healthy lungs and healthy air.
Donate Now.