Asthma Research | American Lung Association

Asthma Research

Asthma research helps us understand how the disease is caused, how it develops and how it is best treated. Research can improve the quality of everyday life for those diagnosed with asthma.

The American Lung Association is committed to funding asthma research. Our Awards and Grants Program seeks out top-notch researchers at important career crossroads to gain long-term commitment to lung health and disease research. Without the life-long dedication of lung researchers, important and much needed discoveries would be impossible. In addition to the Awards and Grants Program, the Lung Association funds the Airways Clinical Research Centers Network, which implements patient-centered clinical trials, and has helped to change the nature of asthma patient care since its inception in 2000.

Some of the current topics American Lung Association funded researchers are investigating include the regulation of lung inflammation in asthma, the immune system's role in asthma, genes important in controlling the immune system's response in allergic asthma and the effect of mold in the lungs on severe asthma. All of these studies could lead to improved therapy for people with asthma.

Thanks to the medical breakthroughs led by Lung Association researchers and their colleagues, our researchers have made significant contributions to the field of asthma. Below are some of our current asthma researchers and their studies. Learn more at Research Awards Nationwide.

Asthma Research Studies

See some of the current research projects we are funding:

  • Audreesh Banerjee, MD
    How Class of Drugs Decreases Airway Hyperresponsiveness
  • Nora Barrett, M.D.
    Understanding Role Receptor Involved in Lung Inflammation Plays in Asthma
    American Lung Association researcher Nora Barrett is studying the recently discovered cysLT receptor GPR99 and determine the way in which it controls lung inflammation.
  • Mallar Bhattacharya, MD
    Blunting Airway Constriction in Asthma
  • Delesha Carpenter, PhD
    Using Mobile App to Help Teens Manage Their Asthma
  • Suzanne Cassel, MD
    Blocking Development of Cells Involved in Steroid-Resistant Asthma
  • Sangwoon Chung, Ph.D.
    Deepening Our Understanding of Immune System's Role in Asthma
    American Lung Association researcher Sangwoon Chung is studying a protein called FoxO1, which has a crucial role in a worsening type 2 immune responses.
  • Taylor Doherty, MD
    Seeking Better Understanding of Allergic Asthma
  • David Fedele, PhD
    Helping Overweight or Obese Children With Asthma Improve Their Health
  • Amy Firth, Ph.D.
    Harnessing Power of a Protein to Improve Lung Repair Following Injury
    American Lung Association researcher Amy Firth is studying how Claudin 18.1 influences function of airway stem cells, which are able to differentiate into specialized cell types to promote repair after injury.
  • Magdalena Gorska, MD, PhD
    Importance of Natural Killer Cells in Prenatally-induced Asthma Predisposition
  • Pamela Guerrerio, MD, PhD
    Development of a Novel Treatment for Asthma
  • Jennifer Ingram, PhD
    Exploring the Link Between Asthma and Obesity
  • Sunit Jariwala, M.D.
    Developing and Testing Software Tool to Help Manage Children's Asthma
    American Lung Association researcher Sunit Jariwala is expanding the existing ASTHMA-Educator software program to include pediatric patients to investigate improved asthma outcomes, patient satisfaction and patient knowledge.
  • Hong Ji, Ph.D.
    Seeking Personalized Treatment for Severe Asthma in Children
    American Lung Association researcher Hong Ji is identifying biological mechanisms that switch genes on and off for difficult-to-treat childhood asthma and investigate how they contribute to the diversity of patients' disease and response to treatment.
  • Ian Lewkowich, PhD
    Why Do Regulatory T Cells Not Work in People with Allergic Asthma?
  • Joshua Mezrich, MD
    Preventing Environmentally Triggered Asthma Flareups
  • Terumi Midoro-Horiuti, MD, PhD
    Can Prenatal Exposure to BPA Increase Asthma Risk?
  • Amit Parulekar, M.D.
    Effect of Mold in the Lungs on Severe Asthma
    American Lung Association researcher Amit Parulekar is studying how allergy to fungi or having fungi in the lungs may lead to more severe asthma, and will test a new method of identifying fungi in the lungs.
  • Wanda Phipatanakul, MD
    Environmental Intervention in Urban Schools and Childhood Asthma
  • Amanda Poholek, Ph.D.
    Protein Holds Clue to Allergic Airway Inflammation
    American Lung Association researcher Amanda Poholek is investigating the environmental factors that lead to the activation of Blimp-1 and how Blimp-1 causes T cells to drive allergic asthma.

Airways Clinical Research Centers

The American Lung Association Airways Clinical Research Centers (ACRC) Network is the nation's largest not-for-profit network of clinical research centers dedicated to asthma and chronic obstructive pulmonary disease (COPD) treatment research, attracting some of the best investigators nationwide. The ACRC Network conducts large clinical trials that will directly impact patient care for COPD and asthma. See where our centers are located and learn more about some of the important research findings from the ACRC.

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