Lobelia Samavati

Spotlight on Research: Lobelia Samavati at Wayne State University, Detroit, MI.

Funded with a Biomedical Research Grant, her project is: How Immune System Works Differently in Sarcoidosis.

Sarcoidosis is an inflammatory disorder that can affect multiple organs throughout the body. It is unknown what causes the disease and its course and outcome are difficult to predict in each individual patient.

Immune protein cells in the body are equipped to recognize these invaders, triggering an inflammatory response in an attempt to kill the invading foreign pathogens.

In healthy individuals, inflammation shuts down once an infection is fought off; however, this process remains sustained in sarcoidosis patients.

Dr. Samavati will investigate why these immune proteins work differently and how the inflammatory process continues to be activated in sarcoidosis patients compared to healthy individuals. The findings may lead to more effective drug therapies.